Drug Information
Drug General Information | Top | |||
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Drug ID |
D0R8IQ
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Drug Name |
WY-46016
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Synonyms |
104325-55-5; 3-(2-Quinolinylmethoxy)benzeneacetic acid; Wy-46016; WY-46,016; AC1L2TZC; 2-[3-(quinolin-2-ylmethoxy)phenyl]acetic acid; [3-(Quinolin-2-ylmethoxy)-phenyl]-acetic acid; CHEMBL310611; SCHEMBL9053241; CTK8G4858; DTXSID00146391; VTTJDSVAGYOMKY-UHFFFAOYSA-N; ZINC5162878; 3-(2-Quinolinylmethoxy)phenylacetic acid; 3-[(2-Quinolinyl)methoxy]benzeneacetic acid; Benzeneacetic acid, 3-(2-quinolinylmethoxy)-
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H15NO3
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Canonical SMILES |
C1=CC=C2C(=C1)C=CC(=N2)COC3=CC=CC(=C3)CC(=O)O
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InChI |
1S/C18H15NO3/c20-18(21)11-13-4-3-6-16(10-13)22-12-15-9-8-14-5-1-2-7-17(14)19-15/h1-10H,11-12H2,(H,20,21)
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InChIKey |
VTTJDSVAGYOMKY-UHFFFAOYSA-N
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CAS Number |
CAS 104325-55-5
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Leukotriene CysLT1 receptor (CYSLTR1) | Target Info | Modulator | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
IL4 Signaling Pathway | ||||
IL3 Signaling Pathway | ||||
Pathway Interaction Database | Endothelins | |||
Reactome | Leukotriene receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides.Potent orally active leukotriene D4 antagonists of novel structure.J Med Chem.1990 Jan;33(1):240-5. |
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