Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R4KE
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| Former ID |
DNC006713
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| Drug Name |
2-(4-fluorophenylsulfonamido)-1-naphthoic acid
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| Synonyms |
sulfonamide compound, 10; CHEMBL212006; SCHEMBL3982656; BDBM17604; 2-[(4-fluorobenzene)sulfonamido]naphthalene-1-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H12FNO4S
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| Canonical SMILES |
C1=CC=C2C(=C1)C=CC(=C2C(=O)O)NS(=O)(=O)C3=CC=C(C=C3)F
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| InChI |
1S/C17H12FNO4S/c18-12-6-8-13(9-7-12)24(22,23)19-15-10-5-11-3-1-2-4-14(11)16(15)17(20)21/h1-10,19H,(H,20,21)
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| InChIKey |
KIYWIXCUCALPGQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Methionine aminopeptidase 2 (METAP2) | Target Info | Inhibitor | [1] |
| Reactome | Inactivation, recovery and regulation of the phototransduction cascade | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3574-7. | |||
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