Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0R2HJ
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| Former ID |
DNC012305
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| Drug Name |
Isoquinoline-3-carboxylic acid methyl ester
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| Synonyms |
methyl isoquinoline-3-carboxylate; 27104-73-0; Methyl 3-isoquinolinecarboxylate; Isoquinoline-3-carboxylic acid methyl ester; 3-Isoquinolinecarboxylic acid, methyl ester; MFCD00075138; PubChem16888; AC1LDU8C; AC1Q5ZLC; Maybridge1_001945; ACMC-1CRQ5; KSC497K1B; SCHEMBL214090; CHEMBL416152; 3-(Methoxycarbonyl)isoquinoline; Methylisoquinoline-3-carboxylate; KS-00000GIP; HMS547A09; CTK3J7510; DTXSID10352385; MolPort-000-141-870; ZBCGBIZQNMVMPC-UHFFFAOYSA-N; methyl isoquinoline-3-carbo-xylate; ZINC132552; BCP05782; ANW-48722; RW2951
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H9NO2
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| Canonical SMILES |
COC(=O)C1=CC2=CC=CC=C2C=N1
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| InChI |
1S/C11H9NO2/c1-14-11(13)10-6-8-4-2-3-5-9(8)7-12-10/h2-7H,1H3
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| InChIKey |
ZBCGBIZQNMVMPC-UHFFFAOYSA-N
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| CAS Number |
CAS 27104-73-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore. J Med Chem. 1988 Sep;31(9):1854-61. | |||
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