Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QS2N
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| Former ID |
DNC013588
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| Drug Name |
3hydroxy-1-methyl-1-phenylurea
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| Synonyms |
CHEMBL262340; N'-hydroxy-N-methyl-N-phenylurea; 13262-41-4; 1-Methyl-1-phenyl-3-hydroxyurea; BDBM50377110
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H10N2O2
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| Canonical SMILES |
CN(C1=CC=CC=C1)C(=O)NO
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| InChI |
1S/C8H10N2O2/c1-10(8(11)9-12)7-5-3-2-4-6-7/h2-6,12H,1H3,(H,9,11)
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| InChIKey |
UDJKPENTLREIMW-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3607-10. | |||
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