Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QH0B
|
|||
| Former ID |
DNC000611
|
|||
| Drug Name |
EPI-2010
|
|||
| Drug Type |
Antisense drug
|
|||
| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Discontinued in Phase 2 | [1] | |
| Therapeutic Class |
Antisense
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | ADORA1 messenger RNA (ADORA1 mRNA) | Target Info | . | [2] |
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009338) | |||
| REF 2 | RASONs: a novel antisense oligonucleotide therapeutic approach for asthma. Expert Opin Biol Ther. 2001 Nov;1(6):979-83. | |||
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