Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q7MA
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| Former ID |
DIB013503
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| Drug Name |
Cefiderocol
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| Synonyms |
Cephalosporin, GSK2696266; S-649266
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| Drug Type |
Small molecular drug
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| Indication | Hospital-acquired pneumonia [ICD-11: CA40.Z] | Approved | [1] | |
| Urinary tract infection [ICD-11: GC08; ICD-10: N39, N39.0] | Approved | [1] | ||
| Ventilator-associated pneumonia [ICD-11: PK81.0] | Approved | [1] | ||
| Healthcare-associated pneumonia [ICD-11: CA00-CA40] | Phase 3 | [2] | ||
| Company |
Glaxosmithkline; shionogi
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| Structure |
 |
Download2D MOL |
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| Formula |
C30H34ClN7O10S2
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| Canonical SMILES |
CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4(CCCC4)CCNC(=O)C5=C(C(=C(C=C5)O)O)Cl)C(=O)[O-]
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| InChI |
1S/C30H34ClN7O10S2/c1-30(2,28(46)47)48-36-19(16-13-50-29(32)34-16)24(42)35-20-25(43)37-21(27(44)45)14(12-49-26(20)37)11-38(8-3-4-9-38)10-7-33-23(41)15-5-6-17(39)22(40)18(15)31/h5-6,13,20,26H,3-4,7-12H2,1-2H3,(H7-,32,33,34,35,36,39,40,41,42,44,45,46,47)/t20-,26-/m1/s1
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| InChIKey |
DBPPRLRVDVJOCL-FQRUVTKNSA-N
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| CAS Number |
CAS 1225208-94-5
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020 | |||
| REF 2 | ClinicalTrials.gov (NCT02714595) Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens (CREDIBLE - CR). U.S. National Institutes of Health. | |||
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