Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q7GG
|
|||
| Former ID |
DNC000216
|
|||
| Drug Name |
Anthramycin
|
|||
| Synonyms |
Antramycin; ANTHRAMYCIN; Anthramycin [USAN]; C16H17N3O4; Anthramycin (USAN); Antramycinum [INN-Latin]; Antramycine [INN-French]; Antramicina [INN-Spanish]; Antramycin (INN); Ro 5-9000; 4803-27-4; Antibiotic PBA; (E)-5,10,11,11a-Tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)-benzodiazepine-2-acrylamide; AC1NSJTB; AC1Q5IYM; SCHEMBL4513; CHEMBL39373; 1H-Pyrrolo(2,1-c)(1,4)benzodiazepine-2-acrylamide, 5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-, (E)-; 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihyd
Click to Show/Hide
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C16H17N3O4
|
|||
| Canonical SMILES |
CC1=C(C2=C(C=C1)C(=O)N3C=C(CC3C(N2)O)C=CC(=O)N)O
|
|||
| InChI |
1S/C16H17N3O4/c1-8-2-4-10-13(14(8)21)18-15(22)11-6-9(3-5-12(17)20)7-19(11)16(10)23/h2-5,7,11,15,18,21-22H,6H2,1H3,(H2,17,20)/b5-3+
|
|||
| InChIKey |
VGQOVCHZGQWAOI-HWKANZROSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Penicillin binding protein (Bact PBP) | Target Info | . | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-A-A-C-G-T-T-G-G and a molecular explanation of specificity. Biochemistry. 1994 Nov 22;33(46):13593-610. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.