Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q6PI
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| Former ID |
DNC012267
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| Drug Name |
PHENETHYLAMINE
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| Synonyms |
Phenethylamine; 2-phenylethylamine; 2-Phenylethanamine; 64-04-0; Benzeneethanamine; phenylethylamine; 2-Phenethylamine; beta-phenylethylamine; beta-Phenethylamine; 1-Amino-2-phenylethane; beta-Aminoethylbenzene; (2-Aminoethyl)benzene; 2-Amino-1-phenylethane; 1-Phenyl-2-aminoethane; Ethylamine, 2-phenyl-; Ethanamine, 2-phenyl-; 2-Phenylethan-1-Amine; 1-Phenyl-2-amino-athan; 2-Fenylethylamin; 2-Amino-fenylethan; 2-Fenylethylamin [Czech]; PHENETHYLAMINE, BETA; 2-Amino-fenylethan [Czech]; beta-Phenylaethylamin [German]
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H11N
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| Canonical SMILES |
C1=CC=C(C=C1)CCN
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| InChI |
1S/C8H11N/c9-7-6-8-4-2-1-3-5-8/h1-5H,6-7,9H2
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| InChIKey |
BHHGXPLMPWCGHP-UHFFFAOYSA-N
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| CAS Number |
CAS 64-04-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7711, 75923, 608001, 833519, 833521, 839990, 3135776, 5482019, 8144848, 8150920, 10509252, 10531461, 14747570, 24847881, 24854450, 24865438, 24865867, 24887854, 24887855, 24901561, 26756723, 30280509, 32040725, 33286030, 36523320, 46393246, 46393335, 46393337, 47193684, 49661414, 49718670, 49856894, 57320659, 57652878, 57652879, 75745031, 80953779, 85165171, 87574348, 88519487, 92298625, 92729694, 103185023, 103812726, 104296483, 104667507, 117531353, 117531423, 118307932, 124811907
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| ChEBI ID |
CHEBI:18397
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2144). | |||
| REF 2 | Exploring the relationship between binding modes of 9-(aminomethyl)-9,10-dihydroanthracene and cyproheptadine analogues at the 5-HT2A serotonin rec... Bioorg Med Chem Lett. 2001 Feb 26;11(4):563-6. | |||
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