Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Q4SJ
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Former ID |
DNC002081
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Drug Name |
ISIS 134607
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Drug Type |
Antisense drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Company |
Isis Pharmaceuticals
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Target and Pathway | Top | |||
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Target(s) | Caspase 6 messenger RNA (CASP6 mRNA) | Target Info | . | [1] |
KEGG Pathway | Apoptosis | |||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | FAS signaling pathway | |||
Pathway Interaction Database | Direct p53 effectors | |||
p75(NTR)-mediated signaling | ||||
C-MYB transcription factor network | ||||
HIV-1 Nef: Negative effector of Fas and TNF-alpha | ||||
Caspase Cascade in Apoptosis | ||||
Reactome | Apoptotic cleavage of cellular proteins | |||
Caspase-mediated cleavage of cytoskeletal proteins | ||||
WikiPathways | Apoptosis Modulation by HSP70 | |||
FAS pathway and Stress induction of HSP regulation | ||||
Apoptosis | ||||
Parkinsons Disease Pathway | ||||
Apoptotic execution phase | ||||
Apoptosis Modulation and Signaling |
References | Top | |||
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REF 1 | US patent application no. 6,566,135, Antisense modulation of caspase 6 expression. |
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