Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q3WP
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| Former ID |
DIB004551
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| Drug Name |
MEDI-553
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| Synonyms |
B-cell depleting anti-CD22 monoclonal antibody, Cellective; B-cell depleting anti-CD22 monoclonal antibody, MedImmune
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| Drug Type |
Antibody
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| Indication | Autoimmune diabetes [ICD-11: 5A10] | Investigative | [1] | |
| Company |
Cellective Therapeutics Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | B-cell receptor CD22 (CD22) | Target Info | . | [1] |
| KEGG Pathway | Cell adhesion molecules (CAMs) | |||
| Hematopoietic cell lineage | ||||
| B cell receptor signaling pathway | ||||
| Panther Pathway | B cell activation | |||
| Pathway Interaction Database | BCR signaling pathway | |||
| Reactome | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | |||
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | ||||
| WikiPathways | B Cell Receptor Signaling Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2786). | |||
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