Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q0SZ
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| Former ID |
DIB010445
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| Drug Name |
OLAMUFLOXACIN MESILATE
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| Synonyms |
HSR-903; Olamufloxacin mesilate; (-)-5-Amino-7-[7(S)-amino-5-azaspiro[2.4]hept-5-yl]-1-cyclopropyl-6-fluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Discontinued in Phase 3 | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C21H27FN4O6S
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| Canonical SMILES |
CC1=C2C(=C(C(=C1N3CC(C4(C3)CC4)N)F)N)C(=O)C(=CN2C5CC5)C(=O)O.CS(=O)(=O)O
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| InChI |
1S/C20H23FN4O3.CH4O3S/c1-9-16-13(18(26)11(19(27)28)6-25(16)10-2-3-10)15(23)14(21)17(9)24-7-12(22)20(8-24)4-5-20;1-5(2,3)4/h6,10,12H,2-5,7-8,22-23H2,1H3,(H,27,28);1H3,(H,2,3,4)/t12-;/m1./s1
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| InChIKey |
QCRMQMNCFYYEFX-UTONKHPSSA-N
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| CAS Number |
CAS 167888-07-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
635280, 10308510, 14902764, 14902765, 38929179, 57405658, 80353290, 87325346, 103144056, 109722639, 117542429, 118845573, 126681675, 128477041, 135132658, 143337029, 152047048, 160707714, 162801117, 164829840, 174549155, 176224977, 179150048, 184546248, 198988613, 223554844, 223661290, 223801165, 228023447
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial DNA gyrase (Bact gyrase) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006301) | |||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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