Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0PF8B
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| Former ID |
DIB006960
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| Drug Name |
PEDF gene therapy
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| Synonyms |
AdPEDF; AdGVPEDF.11D; PEDF gene therapy (ophthalmic); PEDF gene therapy (ophthalmic), GenVec; Pigment epithelium-derived factor gene therapy, GenVec
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| Indication | Macular degeneration [ICD-11: 9B78.3; ICD-10: H35.3; ICD-9: 362.5] | Phase 1 | [1] | |
| Company |
GenVec Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Pigment epithelium-derived factor (SERPINF1) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00109499) Study of AdGVPEDF.11D in Neovascular Age-related Macular Degeneration (AMD). U.S. National Institutes of Health. | |||
| REF 2 | Adenovector pigment epithelium-derived factor (AdPEDF) delivery for wet age-related macular degeneration. Retina. 2005 Dec;25(8 Suppl):S48-S49. | |||
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