Drug Information
Drug General Information | Top | |||
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Drug ID |
D0P9YU
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Former ID |
DNC012083
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Drug Name |
(1-Amino-2-phenyl-ethyl)-phosphinic acid
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Synonyms |
CHEMBL37846; 80744-66-7; (1-AMINO-2-PHENYLETHYL)PHOSPHINIC ACID; Phosphinic acid, (1-amino-2-phenylethyl)-; AC1O49RT; MLS004256549; SCHEMBL3862224; CTK5E8078; DTXSID90422994; APQRSTHZZSRXIS-UHFFFAOYSA-N; AKOS006273173; SMR003081569; (1-amino-2-phenylethyl)-hydroxy-oxophosphanium; Phosphinic acid,(1-amino-2-phenylethyl)- (9CI)
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C8H10NO2P
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Canonical SMILES |
C1=CC=C(C=C1)CC(=N)P(O)O
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InChI |
1S/C8H10NO2P/c9-8(12(10)11)6-7-4-2-1-3-5-7/h1-5,9-11H,6H2
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InChIKey |
SBTPFRFIHZOOQM-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Aminopeptidase N (ANPEP) | Target Info | Inhibitor | [1] |
BioCyc | Glutathione-mediated detoxification | |||
KEGG Pathway | Glutathione metabolism | |||
Metabolic pathways | ||||
Renin-angiotensin system | ||||
Hematopoietic cell lineage | ||||
Pathwhiz Pathway | Glutathione Metabolism | |||
Pathway Interaction Database | C-MYB transcription factor network | |||
Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
WikiPathways | Metabolism of Angiotensinogen to Angiotensins | |||
Cardiac Progenitor Differentiation | ||||
miR-targeted genes in squamous cell - TarBase | ||||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in leukocytes - TarBase | ||||
Glutathione metabolism |
References | Top | |||
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REF 1 | Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1511-6. |
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