Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P9IA
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| Former ID |
DIB019774
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| Drug Name |
dolichol phosphate
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| Synonyms |
Dolichol-P; dolichol-phosphate; dolichyl-phosphate; Dolychol phosphate; Dolichol-PO4; AC1NQWWQ; GTPL3214; [(6E)-3,7,11-trimethyldodeca-6,10-dienyl] dihydrogen phosphate; {[(6E)-3,7,11-trimethyldodeca-6,10-dien-1-yl]oxy}phosphonic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C15H29O4P
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| Canonical SMILES |
CC(CCC=C(C)CCC=C(C)C)CCOP(=O)(O)O
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| InChI |
1S/C15H29O4P/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-19-20(16,17)18/h7,9,15H,5-6,8,10-12H2,1-4H3,(H2,16,17,18)/b14-9+
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| InChIKey |
DZHSRPJGCZHWOM-NTEUORMPSA-N
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| CAS Number |
CAS 34457-14-2
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mevalonate kinase (MVK) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A defect in dolichol phosphate biosynthesis causes a new inherited disorder with death in early infancy. Am J Hum Genet. 2007 Mar;80(3):433-40. | |||
| REF 2 | Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways. J Lipid Res. 1997 Nov;38(11):2216-23. | |||
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