Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P8TS
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| Former ID |
DIB001782
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| Drug Name |
Eperisone
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| Synonyms |
EMPP; Myonal; Myorelark; E-0646; E-2000; E-646; Eperisone (transdermal patch); Eperisone (oral), Eisai; Eperisone (transdermalpatch), Eisai; E-2000 (oral), Eisai; E-2000 (transdermal patch), Eisai
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| Drug Type |
Small molecular drug
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| Indication | Muscle spasm [ICD-11: MB47.3; ICD-10: R25.2] | Phase 3 | [1] | |
| Company |
Eisai Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H25NO
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| Canonical SMILES |
CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2
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| InChI |
1S/C17H25NO/c1-3-15-7-9-16(10-8-15)17(19)14(2)13-18-11-5-4-6-12-18/h7-10,14H,3-6,11-13H2,1-2H3
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| InChIKey |
SQUNAWUMZGQQJD-UHFFFAOYSA-N
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| CAS Number |
CAS 64840-90-0
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:77070
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel (Cav) | Target Info | Modulator | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02040415) Phase 3 Study to Evaluate the Efficacy and Safety of DW-1030 and Eperisone HCl in Acute Back Pain Patients. U.S. National Institutes of Health. | |||
| REF 2 | Suppression of calcium current in a snail neurone by eperisone and its analogues. Eur J Pharmacol. 1989 Sep 22;168(3):299-305. | |||
| REF 3 | Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan. Neurochem Int. 2009 Jul;54(8):526-34. | |||
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