Drug Information
Drug General Information | Top | |||
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Drug ID |
D0P5BY
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Former ID |
DNC006135
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Drug Name |
N-(cyanomethyl)cyclohex-1-ene-1-carboxamide
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Synonyms |
1-Cyclohexene-1-carboxamide, N-(cyanomethyl)-; 875142-19-1
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C9H12N2O
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Canonical SMILES |
C1CCC(=CC1)C(=O)NCC#N
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InChI |
1S/C9H12N2O/c10-6-7-11-9(12)8-4-2-1-3-5-8/h4H,1-3,5,7H2,(H,11,12)
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InChIKey |
ZVHMBSSCZBPAIY-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cathepsin K (CTSK) | Target Info | Inhibitor | [1] |
KEGG Pathway | Lysosome | |||
Osteoclast differentiation | ||||
Toll-like receptor signaling pathway | ||||
Rheumatoid arthritis | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
RANKL Signaling Pathway | ||||
IL2 Signaling Pathway | ||||
Reactome | Collagen degradation | |||
Degradation of the extracellular matrix | ||||
Activation of Matrix Metalloproteinases | ||||
Trafficking and processing of endosomal TLR | ||||
MHC class II antigen presentation | ||||
WikiPathways | RANKL/RANK Signaling Pathway | |||
Osteoclast Signaling |
References | Top | |||
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REF 1 | Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K. J Med Chem. 2006 Feb 9;49(3):1066-79. |
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