Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P4MT
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| Former ID |
DAP000992
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| Drug Name |
Oxamniquine
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| Synonyms |
Mansil; Oxaminiquine; Oxamniquina; Oxamniquinum; Vansil; UK 4261; UK 4271; Mansil (TN); Oxamniquina [INN-Spanish]; Oxamniquinum [INN-Latin]; UK-4271; Vansil (TN); Oxamniquine (USAN/INN); Oxamniquine [USAN:BAN:INN]; {2-[(Isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol; [7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl]methanol; (2-{[(1-methylethyl)amino]methyl}-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl)methanol; 1,2,3,4-Tetrahydro-2-(((1-methylethyl)amino)methyl)-7-nitro-6-quinolinemethanol; 1,2,3,4-Tetrahydro-2-((isopropylamino)methyl)-7-nitro-6-quinolinemethanol; 1,2,3,4-Tetrahydro-2-[(isopropylamino)methyl]-7-nitro-6-quinolinemethanol; 2-((Isopropylamino)methyl)-7-nitro-1,2,3,4-tetrahydro-6-quinolinemethanol; 2-(Isopropylaminomethyl)-7-nitro-1,2,3,4-tetrahydroquinoline-6-methanol; 6-Hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
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| Drug Type |
Small molecular drug
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| Indication | Schistosomiasis [ICD-11: 1F86; ICD-10: B65, B65.9; ICD-9: 120] | Approved | [1] | |
| Therapeutic Class |
Schistosomicides
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| Company |
Pfizer Pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C14H21N3O3
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| Canonical SMILES |
CC(C)NCC1CCC2=CC(=C(C=C2N1)[N+](=O)[O-])CO
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| InChI |
1S/C14H21N3O3/c1-9(2)15-7-12-4-3-10-5-11(8-18)14(17(19)20)6-13(10)16-12/h5-6,9,12,15-16,18H,3-4,7-8H2,1-2H3
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| InChIKey |
XCGYUJZMCCFSRP-UHFFFAOYSA-N
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| CAS Number |
CAS 21738-42-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9548, 463879, 606338, 5396325, 7434785, 7847526, 7980212, 8152829, 11467054, 11468174, 11486808, 14799596, 22395920, 26665195, 29223701, 46508789, 48334689, 48416357, 50042967, 51780913, 57322349, 92126057, 103222043, 103914643, 104306910, 124799447, 126407963, 134222524, 134338262, 134994440, 137241860, 144204144, 160964430, 163077656, 178126512, 179149405, 223443758, 226429093, 241040351, 249935262
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| ChEBI ID |
CHEBI:78416
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| SuperDrug ATC ID |
P02BA02
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| SuperDrug CAS ID |
cas=021738421
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Schistosoma Deoxyribonucleic acid (Schist DNA) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Opportunities and challenges in antiparasitic drug discovery. Nat Rev Drug Discov. 2005 Sep;4(9):727-40. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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