Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P2TS
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| Former ID |
DNC007549
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| Drug Name |
UK-383367
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| Synonyms |
UK 383367; 348622-88-8; UK-383367; CHEMBL226630; 5-[(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl]-1,2,4-oxadiazole-3-carboxamide; (R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamide; ARJCBSRIPGJMAD-LLVKDONJSA-N; UK383367; 5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazole-3-carboxamide; MLS006011234; SCHEMBL6430715; CTK8F1316; SYN3014; DTXSID30431303; MolPort-016-633-322; ZINC3818556; s2224; BDBM50216795; AKOS024458022; SB19579; RL03300; CS-0414
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H24N4O4
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| Canonical SMILES |
C1CCC(CC1)CCCC(CC(=O)NO)C2=NC(=NO2)C(=O)N
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| InChI |
1S/C15H24N4O4/c16-13(21)14-17-15(23-19-14)11(9-12(20)18-22)8-4-7-10-5-2-1-3-6-10/h10-11,22H,1-9H2,(H2,16,21)(H,18,20)/t11-/m1/s1
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| InChIKey |
ARJCBSRIPGJMAD-LLVKDONJSA-N
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| CAS Number |
CAS 348622-88-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bone morphogenetic protein 1 (BMP1) | Target Info | Inhibitor | [1] |
| Panther Pathway | TGF-beta signaling pathway | |||
| Reactome | Degradation of the extracellular matrix | |||
| Collagen biosynthesis and modifying enzymes | ||||
| Anchoring fibril formation | ||||
| WikiPathways | Cardiac Progenitor Differentiation | |||
| Adipogenesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically a... Bioorg Med Chem Lett. 2008 Dec 15;18(24):6562-7. | |||
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