Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P2NN
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| Former ID |
DNC001214
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| Drug Name |
Rimantadine isomer 1
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| Synonyms |
Rimantadine hydrochloride; 1501-84-4; Flumadine; Rimantadine HCL; Meradane; 1-(1-ADAMANTYL)ETHYLAMINE HYDROCHLORIDE; 1-(1-Aminoethyl)adamantane hydrochloride; alpha-Methyl-1-adamantanemethylamine hydrochloride; 1-(Adamantan-1-yl)ethanamine hydrochloride; Algirem; Meradan; Roflual; Oclovir; 1-(1-adamantyl)ethanamine hydrochloride; EXP 126; JP 61; Rimantadine (hydrochloride); Remantadine hydrochloride; NSC 206764; C12H22ClN; MLS000069661; CHEBI:8865; Adamantane, 1-(1-aminoethyl)-, hydrochloride; Rimantadine hydrochloride [USAN]
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2], [3] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H22ClN
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| Canonical SMILES |
CC(C12CC3CC(C1)CC(C3)C2)N.Cl
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| InChI |
1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H
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| InChIKey |
OZBDFBJXRJWNAV-UHFFFAOYSA-N
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| CAS Number |
CAS 1501-84-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
10294, 565978, 3211711, 7847965, 8161372, 11532902, 12012867, 24864331, 26543526, 26661904, 29283141, 49864988, 57328902, 80065664, 81091325, 85175159, 87229484, 87575628, 87619861, 92710515, 99351123, 103675814, 103770338, 104170172, 104336389, 115354336, 117444419, 124639173, 125341572, 125536529, 126603577, 126631804, 126664695, 130912463, 131356247, 131549820, 134340431, 134978889, 135571730, 135709693, 136897159, 136912726, 136991469, 137089170, 143394411, 143500265, 143524166, 144075887, 144098414, 144205265
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| ChEBI ID |
CHEBI:8865
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| ADReCS Drug ID | BADD_D01945 | |||
| SuperDrug ATC ID |
J05AC02
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| SuperDrug CAS ID |
cas=013392284
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Influenza M2 protein (Influ M) | Target Info | Inhibitor | [1], [2], [3] |
| WikiPathways | Influenza Life Cycle | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25. | |||
| REF 2 | Heterocyclic rimantadine analogues with antiviral activity. Bioorg Med Chem. 2003 Dec 1;11(24):5485-92. | |||
| REF 3 | Are the 2-isomers of the drug rimantadine active anti-influenza A agents Antivir Chem Chemother. 2003 May;14(3):153-64. | |||
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