Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P2DB
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| Former ID |
DNC012321
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| Drug Name |
7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene
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| Synonyms |
CHEMBL301605; 7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene; 7,12-dihydropyrido[3,2-b:5,4-b']diindole; NCI60_006891; AC1L7HBP; AC1Q4YR3; CTK5J6980; ZINC12941871
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H11N3
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| Canonical SMILES |
C1=CC=C2C(=C1)C3=C4C(=NC=C3N2)C5=CC=CC=C5N4
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| InChI |
1S/C17H11N3/c1-3-7-12-10(5-1)15-14(19-12)9-18-16-11-6-2-4-8-13(11)20-17(15)16/h1-9,19-20H
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| InChIKey |
UFTKNTUWDMJOIX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of 7,12-dihydropyrido[3,4-b:5,4-b']diindoles. A novel class of rigid, planar benzodiazepine receptor ligands. J Med Chem. 1987 Mar;30(3):456-8. | |||
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