Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P2CS
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| Former ID |
DNC004420
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| Drug Name |
EVANS BLUE
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| Synonyms |
tetrasodium (6E)-4-amino-6-[[4-[4-[(2Z)-2-(8-amino-1-oxo-5,7-disulfonatonaphthalen-2-ylidene)hydrazinyl]-3-methylphenyl]-2-methylphenyl]hydrazinylidene]-5-oxonaphthalene-1,3-disulfonate; AC1NUWHB; AC1O426Q; AN-23389; tetrasodium (6E)-4-amino-6-[[4-[4-[(2Z)-2-(8-amino-1-oxo-5,7-disulfonato-2-naphthylidene)hydrazino]-3-methyl-phenyl]-2-methyl-phenyl]hydrazono]-5-oxo-naphthalene-1,3-disulfonate; 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino-5-hydroxy-1,3-naphthalenedisulphonic acid]tetrasodium sa
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| Drug Type |
Small molecular drug
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| Indication | Abdominal aortic aneurysm [ICD-11: BD50.4; ICD-10: I71.3, I71.4] | Approved | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C34H24N6Na4O14S4
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| Canonical SMILES |
CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C3)C(=CC(=C4N)S(=O)(=O)[O-])S(=O)(=O)[O-])O)C)N=NC5=C(C6=C(C=C5)C(=CC(=C6N)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+].[Na+].[Na+]
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| InChI |
1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4
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| InChIKey |
ATNOAWAQFYGAOY-UHFFFAOYSA-J
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| CAS Number |
CAS 314-13-6
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:82467
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serum albumin (ALB) | Target Info | Modulator | [1] |
| Pathway Interaction Database | FOXA2 and FOXA3 transcription factor networks | |||
| Reactome | Platelet degranulation | |||
| Recycling of bile acids and salts | ||||
| HDL-mediated lipid transport | ||||
| Scavenging of heme from plasma | ||||
| WikiPathways | Human Complement System | |||
| Binding and Uptake of Ligands by Scavenger Receptors | ||||
| Lipid digestion, mobilization, and transport | ||||
| Transport of vitamins, nucleosides, and related molecules | ||||
| Bile acid and bile salt metabolism | ||||
| Folate Metabolism | ||||
| Vitamin B12 Metabolism | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954. | |||
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