Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0P0EP
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| Former ID |
DNC003134
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| Drug Name |
6-Hydroxyuridine-5'-Phosphate
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| Synonyms |
6-hydroxy-UMP; 6-HYDROXYURIDINE-5'-PHOSPHATE; 6-hydroxyuridine 5'-(dihydrogen phosphate); CHEMBL383923; 29741-00-2; Prfb acid; 1lor; 1dqx; 1eix; 6-hydroxyuridine 5'-phosphate; AC1Q69HY; AC1L4PT5; 5'-Uridylic acid,6-hydroxy-; SCHEMBL2130675; 5'-Uridylic acid, 6-hydroxy-; CTK4G3746; DTXSID50183892; Phosphoribofuranosylbarbituric acid; BDBM50199178; 6-Hydroxyuridine 5'-phosphoric acid; DB02890; 6-HYDROXYURIDINE-5''-PHOSPHATE; Barbituric acid ribonucleoside 5'-phosphate; 1-beta-D-ribofuranosyl(3H)pyrimidine-2,4,6-trione 5''-monophosp
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H13N2O10P
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| Canonical SMILES |
C1=C(N(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O)O
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| InChI |
1S/C9H13N2O10P/c12-4-1-5(13)11(9(16)10-4)8-7(15)6(14)3(21-8)2-20-22(17,18)19/h1,3,6-8,13-15H,2H2,(H,10,12,16)(H2,17,18,19)/t3-,6-,7-,8-/m1/s1
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| InChIKey |
UDOBICLZEKUKCV-YXZULKJRSA-N
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| CAS Number |
CAS 29741-00-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mycobacterium Orotidine phosphate decarboxylase (MycB pyrF) | Target Info | Inhibitor | [1] |
| Orotidine 5'-monophosphate decarboxylase (UMPS) | Target Info | Inhibitor | [1] | |
| BioCyc | Superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis | |||
| Superpathway of pyrimidine ribonucleotides de novo biosynthesis | ||||
| UMP biosynthesis | ||||
| KEGG Pathway | Pyrimidine metabolism | |||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| Fluoropyrimidine Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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