Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0OY1V
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| Former ID |
DIB015766
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| Drug Name |
NS-1608
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| Synonyms |
NS 1608; CHEMBL33891; NS-1608; Kinome_784; 160383-80-2; AC1L323R; CHEBI:34878; SureCN1463468; ns1608; SCHEMBL1463468; DTXSID80166870; N-(3-(Trifluoromethyl)phenyl)-N'-(2-hydroxy-5-chlorophenyl)urea; BDBM50158564; AKOS029964740; C13835; 1-(5-chloro-2-hydroxyphenyl)-3-(3-trifluoromethylphenyl)urea; 1-(5-chloro-2-hydroxy-phenyl)-3-[3-(trifluoromethyl)phenyl]urea; 1-(5-Chloro-2-hydroxy-phenyl)-3-(3-trifluoromethyl-phenyl)-urea
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| Drug Type |
Small molecular drug
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| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Terminated | [1] | |
| Company |
NeuroSearch A/S
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| Structure |
 |
Download2D MOL |
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| Formula |
C14H10ClF3N2O2
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| Canonical SMILES |
C1=CC(=CC(=C1)NC(=O)NC2=C(C=CC(=C2)Cl)O)C(F)(F)F
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| InChI |
1S/C14H10ClF3N2O2/c15-9-4-5-12(21)11(7-9)20-13(22)19-10-3-1-2-8(6-10)14(16,17)18/h1-7,21H,(H2,19,20,22)
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| InChIKey |
KRHJDJMOIKRPNN-UHFFFAOYSA-N
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| CAS Number |
CAS 160383-80-2
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:34878
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006351) | |||
| REF 2 | Modulation of the Ca(2+)-dependent K+ channel, hslo, by the substituted diphenylurea NS 1608, paxilline and internal Ca2+. Neuropharmacology. 1996;35(7):903-14. | |||
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