Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OY1R
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| Former ID |
DIB018930
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| Drug Name |
aza-THIP
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| Synonyms |
654666-65-6; 1,2,4,5,6,7-Hexahydro-3H-pyrazolo[3,4-c]pyridin-3-one; 4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-3-ol; 3H-Pyrazolo[3,4-c]pyridin-3-one, 1,2,4,5,6,7-hexahydro-; 1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol; 4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridin-3-ol; aza-THIP; THIP, Aza-; 4,5,6,7-tetrahydropyrazolo[5,4-c]pyridin-3-ol; SCHEMBL2946381; GTPL4143; SCHEMBL16057201; CTK1J6712; BDBM86256; DTXSID20717441; UPMMUUFLHUEUKP-UHFFFAOYSA-N; MolPort-022-468-866; ZINC13859300; AKOS022182337; AKOS022718659; AKOS006351664
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C6H9N3O
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| Canonical SMILES |
C1CNCC2=C1C(=O)NN2
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| InChI |
1S/C6H9N3O/c10-6-4-1-2-7-3-5(4)8-9-6/h7H,1-3H2,(H2,8,9,10)
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| InChIKey |
UPMMUUFLHUEUKP-UHFFFAOYSA-N
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| CAS Number |
CAS 654666-65-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor rho1 (GABRR1) | Target Info | Antagonist | [2] |
| GABA(A) receptor rho2 (GABRR2) | Target Info | Antagonist | [3] | |
| GABA(A) receptor rho3 (GABRR3) | Target Info | Antagonist | [4] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4143). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 420). | |||
| REF 3 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 421). | |||
| REF 4 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 422). | |||
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