Drug Information
Drug General Information | Top | |||
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Drug ID |
D0OR4G
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Drug Name |
Diarylamine and arylheteroarylamine pyrazole derivative 2
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Synonyms |
PMID26609882-Compound-38
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Drug Type |
Small molecular drug
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Company |
Arena Pharmaceuticals, Inc
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Structure |
Download2D MOL |
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Formula |
C16H13BrClN3
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Canonical SMILES |
CN1C(=C(C=N1)Br)C2=CC(=CC=C2)NC3=CC=C(C=C3)Cl
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InChI |
1S/C16H13BrClN3/c1-21-16(15(17)10-19-21)11-3-2-4-14(9-11)20-13-7-5-12(18)6-8-13/h2-10,20H,1H3
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InChIKey |
CEDWMDLRVLLSQK-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Agonist | [1] |
Target's Patent Info | 5-HT 2A receptor (HTR2A) | Target's Patent Info | [1] | |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Novel serotonin receptor 2 (5-HT2R) agonists and antagonists: a patent review (2004-2014).Expert Opin Ther Pat. 2016;26(1):89-106. |
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