Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OA8M
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| Former ID |
DIB020923
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| Drug Name |
SC-19220
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| Synonyms |
SC 19220; SC19220
Click to Show/Hide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C16H14ClN3O3
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| Canonical SMILES |
CC(=O)NNC(=O)N1CC2=CC=CC=C2OC3=C1C=C(C=C3)Cl
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| InChI |
1S/C16H14ClN3O3/c1-10(21)18-19-16(22)20-9-11-4-2-3-5-14(11)23-15-7-6-12(17)8-13(15)20/h2-8H,9H2,1H3,(H,18,21)(H,19,22)
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| InChIKey |
KNURFLJTOUGOOQ-UHFFFAOYSA-N
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| CAS Number |
CAS 19395-87-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
6375884, 7980576, 9645084, 11111793, 11113956, 14826747, 17405653, 24278701, 35637713, 46500470, 47944894, 50104757, 50104758, 53778203, 53790367, 57356934, 71739177, 74458452, 85229991, 85231223, 85787597, 90340966, 91722308, 92303261, 103334571, 112856495, 121361980, 124750232, 124799776, 124881429, 124881430, 125334272, 135651018, 135698406, 136351441, 162022781, 162250186, 163137960, 163565051, 178125964, 179150123, 237693855, 241182229, 241375297, 250136930
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| ChEBI ID |
CHEBI:92916
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E2 receptor EP1 (PTGER1) | Target Info | Antagonist | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Pathways in cancer | ||||
| Panther Pathway | PI3 kinase pathway | |||
| Reactome | Prostanoid ligand receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1922). | |||
| REF 2 | Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. Eur J Pharmacol. 1997 Dec 11;340(2-3):227-41. | |||
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