Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O8PM
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| Former ID |
DNC007637
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| Drug Name |
N,N-bis(cyanomethyl)-3,4-dimethoxybenzamide
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| Synonyms |
N,N-bis(cyanomethyl)-3,4-dimethoxybenzamide; AC1LDLXQ; Cambridge id 5654537; Oprea1_349431; CHEMBL244919; ZINC29912; BDBM23727; MolPort-001-507-799; HMS1584M04; STK002684; AKOS003266947; MCULE-7184403963; ST042963; N,N-bis(cyanomethyl)-3,4-dimethoxybenzamide, 11; SR-01000215998; N~1~,N~1~-bis(cyanomethyl)-3,4-dimethoxybenzamide; SR-01000215998-1
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H13N3O3
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| Canonical SMILES |
COC1=C(C=C(C=C1)C(=O)N(CC#N)CC#N)OC
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| InChI |
1S/C13H13N3O3/c1-18-11-4-3-10(9-12(11)19-2)13(17)16(7-5-14)8-6-15/h3-4,9H,7-8H2,1-2H3
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| InChIKey |
GZUJYYKDHAQDKU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neutrophil elastase (NE) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Transcriptional misregulation in cancer | |||
| Systemic lupus erythematosus | ||||
| Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||
| C-MYB transcription factor network | ||||
| Reactome | Collagen degradation | |||
| Degradation of the extracellular matrix | ||||
| Activation of Matrix Metalloproteinases | ||||
| WikiPathways | Hair Follicle Development: Cytodifferentiation (Part 3 of 3) | |||
| Human Complement System | ||||
| Degradation of collagen | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase. J Med Chem. 2007 Oct 4;50(20):4928-38. | |||
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