Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O7CX
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| Former ID |
DNC014327
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| Drug Name |
4'-Amino-4-hydroxychalcone
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| Synonyms |
CHEMBL383563; 1-(4-aminophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one; 4''-Amino-4-hydroxychalcone; AC1O21K2; SCHEMBL3762443; MolPort-019-723-769; ZINC4099897; SBB099103; BDBM50174839; AN-308/25123008; (2E)-1-(4-aminophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H13NO2
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| Canonical SMILES |
C1=CC(=CC=C1C=CC(=O)C2=CC=C(C=C2)N)O
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| InChI |
1S/C15H13NO2/c16-13-6-4-12(5-7-13)15(18)10-3-11-1-8-14(17)9-2-11/h1-10,17H,16H2
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| InChIKey |
GJKSOGFGWQZGRL-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone. Eur J Med Chem. 2010 May;45(5):2010-7. | |||
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