Drug Information
Drug General Information | Top | |||
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Drug ID |
D0O6ZD
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Former ID |
DNC011338
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Drug Name |
8-acetyl-7-(benzyloxy)-2H-chromen-2-one
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Synonyms |
CHEMBL1290111; 65535-49-1; 8-acetyl-7-(benzyloxy)-2H-chromen-2-one; SCHEMBL7518570; CTK1J6469; DTXSID60555920; BDBM50332028; 8-Acetyl-7-(benzyloxy)-2H-1-benzopyran-2-one; 2H-1-Benzopyran-2-one, 8-acetyl-7-(phenylmethoxy)-
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H14O4
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Canonical SMILES |
CC(=O)C1=C(C=CC2=C1OC(=O)C=C2)OCC3=CC=CC=C3
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InChI |
1S/C18H14O4/c1-12(19)17-15(21-11-13-5-3-2-4-6-13)9-7-14-8-10-16(20)22-18(14)17/h2-10H,11H2,1H3
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InChIKey |
QMLSJCDSHGYBMT-UHFFFAOYSA-N
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CAS Number |
CAS 65535-49-1
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Carbonic anhydrase IX (CA-IX) | Target Info | Inhibitor | [1] |
KEGG Pathway | Nitrogen metabolism | |||
Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
Reactome | Regulation of gene expression by Hypoxia-inducible Factor | |||
Reversible hydration of carbon dioxide | ||||
WikiPathways | Vitamin D Receptor Pathway | |||
Reversible Hydration of Carbon Dioxide | ||||
Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
References | Top | |||
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REF 1 | 7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and X... Bioorg Med Chem Lett. 2010 Dec 15;20(24):7255-8. |
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