Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O6RK
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| Former ID |
DNCL001849
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| Drug Name |
MD-0727
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| Indication | Hypercholesterolaemia [ICD-11: 5C80.0] | Phase 2 | [1] | |
| Company |
Ironwood Pharmaceuticals
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C10H11NO3
|
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| Canonical SMILES |
CCOC(=O)C1=CC=CC(=N1)C(=O)C
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| InChI |
1S/C10H11NO3/c1-3-14-10(13)9-6-4-5-8(11-9)7(2)12/h4-6H,3H2,1-2H3
|
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| InChIKey |
COYXIUHSZNHMAS-UHFFFAOYSA-N
|
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| CAS Number |
CAS 114578-70-0
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholesterol absorption (Chole absorp) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00404001) Study of Oral MD-0727 Administered to Patients With Primary Hypercholesterolemia. U.S. National Institutes of Health. | |||
| REF 2 | Th-P16:297 Early clinical characterization of MD-0727, a novel cholesterol absorption inhibitor, in healthy subjects. Atherosclerosis Supplements Volume 7, Issue 3, 2006, Pages 558-559. | |||
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