Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O3WF
|
|||
| Former ID |
DNC002141
|
|||
| Drug Name |
ISIS 103386
|
|||
| Drug Type |
Antisense drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Company |
Isis Pharmaceuticals
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DUSP8 messenger RNA (DUSP8 mRNA) | Target Info | . | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Pathway Interaction Database | Regulation of p38-alpha and p38-beta | |||
| ATF-2 transcription factor network | ||||
| Reactome | RAF-independent MAPK1/3 activation | |||
| Negative regulation of MAPK pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | US patent application no. 6,482,644, Antisense modulation of dual specific phosphatase 8 expression. | |||
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