Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0O1WJ
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| Former ID |
DIB013329
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| Drug Name |
SR-1001
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| Synonyms |
TH17 cell inhibitor (multiple sclerosis), Scripps
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| Indication | Diabetic retinopathy [ICD-11: 9B71.0; ICD-10: H36.0] | Preclinical | [1] | |
| Multiple sclerosis [ICD-11: 8A40; ICD-9: 340] | Investigative | [2] | ||
| Company |
Scripps Research Institute
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| Structure |
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Download2D MOL |
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| Formula |
C15H13F6N3O4S2
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| Canonical SMILES |
CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
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| InChI |
1S/C15H13F6N3O4S2/c1-7-11(29-12(22-7)23-8(2)25)30(27,28)24-10-5-3-9(4-6-10)13(26,14(16,17)18)15(19,20)21/h3-6,24,26H,1-2H3,(H,22,23,25)
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| InChIKey |
OZBSSKGBKHOLGA-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | RORt Inhibitor-SR1001 Halts Retinal Inflammation, Capillary Degeneration, and the Progression of Diabetic Retinopathy. Int J Mol Sci. 2020 May 17;21(10):3547. | |||
| REF 2 | The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954. | |||
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