Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0NW9G
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| Former ID |
DNC000057
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| Drug Name |
3-(9-Acridinylamino)-5-(hydroxymethyl)aniline (AHMA)
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| Synonyms |
CHEMBL321473; NSC666097; 3-(9-acridinylamino)-5-(hydroxymethyl)aniline; 154310-42-6; [3-(acridin-9-ylamino)-5-aminophenyl]methanol; AC1Q7C6S; AC1L8FG4; SCHEMBL1865418; CTK0E7866; DTXSID30327555; GZHHMAFXYHPHBO-UHFFFAOYSA-N; ZINC3799478; AKOS030584742; NCI60_022917; 3-(9-acridinylamino)-5-hydroxymethylaniline; 3-(acridin-9-yl)amino-5-hydroxymethylaniline; Benzenemethanol, 3-(9-acridinylamino)-5-amino-; [3-(acridin-9-ylamino)-5-amino-phenyl]methanol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H17N3O
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=C3C=CC=CC3=N2)NC4=CC(=CC(=C4)N)CO
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| InChI |
1S/C20H17N3O/c21-14-9-13(12-24)10-15(11-14)22-20-16-5-1-3-7-18(16)23-19-8-4-2-6-17(19)20/h1-11,24H,12,21H2,(H,22,23)
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| InChIKey |
GZHHMAFXYHPHBO-UHFFFAOYSA-N
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| CAS Number |
CAS 154310-42-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase (TOP) | Target Info | Inhibitor | [1] |
| References | Top | |||
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| REF 1 | Crystallization and preliminary X-ray analysis of anti-cancer agent 3-(9-acridinylamino)-5-(hydroxymethyl)aniline complexed with the DNA hexamer d(CGTACG)2. Biochim Biophys Acta. 2003 Jan 3;1625(1):27-9. | |||
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