Drug Information
Drug General Information | Top | |||
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Drug ID |
D0NQ7I
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Former ID |
DNC005191
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Drug Name |
SPONGIADIOXIN A
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Synonyms |
SPONGIADIOXIN A; CHEMBL185828; 329040-77-9; Dibenzo[b,e][1,4]dioxin-1-ol, 3,4,6,8-tetrabromo-; BDBM50150784
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H4Br4O3
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Canonical SMILES |
C1=C(C=C(C2=C1OC3=C(O2)C(=C(C=C3O)Br)Br)Br)Br
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InChI |
1S/C12H4Br4O3/c13-4-1-6(15)10-8(2-4)18-11-7(17)3-5(14)9(16)12(11)19-10/h1-3,17H
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InChIKey |
SSCRQJOLSHUSSG-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] |
BioCyc | Resolvin D biosynthesis | |||
Lipoxin biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Linoleic acid metabolism | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
Pathway Interaction Database | IL4-mediated signaling events | |||
WikiPathways | Arachidonic acid metabolism | |||
Eicosanoid Synthesis |
References | Top | |||
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REF 1 | Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. J Med Chem. 2004 Jul 29;47(16):4060-5. |
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