Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0N9NS
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| Former ID |
DNC010682
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| Drug Name |
(R)-2-(2-naphthamido)-3-m-tolylpropanoic acid
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| Synonyms |
CHEMBL1091064; (R)-2-(2-naphthamido)-3-m-tolylpropanoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H19NO3
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| Canonical SMILES |
CC1=CC(=CC=C1)CC(C(=O)O)NC(=O)C2=CC3=CC=CC=C3C=C2
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| InChI |
1S/C21H19NO3/c1-14-5-4-6-15(11-14)12-19(21(24)25)22-20(23)18-10-9-16-7-2-3-8-17(16)13-18/h2-11,13,19H,12H2,1H3,(H,22,23)(H,24,25)/t19-/m1/s1
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| InChIKey |
ZDRUGIXKFVQOIJ-LJQANCHMSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Rotamase Pin1 (PIN1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | RIG-I-like receptor signaling pathway | |||
| Pathway Interaction Database | p73 transcription factor network | |||
| C-MYC pathway | ||||
| PDGFR-beta signaling pathway | ||||
| p53 pathway | ||||
| Reactome | ISG15 antiviral mechanism | |||
| Negative regulators of RIG-I/MDA5 signaling | ||||
| WikiPathways | ISG15 antiviral mechanism | |||
| RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-based design of novel human Pin1 inhibitors (II). Bioorg Med Chem Lett. 2010 Apr 1;20(7):2210-4. | |||
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