Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0N9DU
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| Former ID |
DIB020052
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| Drug Name |
indirubin derivative E804
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| Synonyms |
indirubin E804; compound 2 [PMID: 21632247]
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NOCCC(CO)O
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosine-protein kinase EIF2AK2 (p68) | Target Info | Inhibitor | [1] |
| Panther Pathway | Apoptosis signaling pathway | |||
| Pathway Interaction Database | Signaling events mediated by TCPTP | |||
| Ceramide signaling pathway | ||||
| PDGFR-beta signaling pathway | ||||
| Reactome | ISG15 antiviral mechanism | |||
| WikiPathways | Type II interferon signaling (IFNG) | |||
| Host Interactions with Influenza Factors | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| Translation Factors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14. | |||
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