Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0N8QO
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| Drug Name |
US10053465, 8
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| Synonyms |
SCHEMBL2395720; CHEMBL3911726; RZUCZMLSGAQMJN-UHFFFAOYSA-N; BDBM246869; US10053465, 8; 4-{3-(Cyanomethyl)- 3-[4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]azetidin-1-yl}-N- [4-fluoro-2- (trifluoromethyl) phenyl]piperidine-1- carboxamide; 4-{3-(cyanomethyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-1-yl}-N-[4-fluoro-2-(trifluoromethyl)phenyl]piperidine-1-carboxamide
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C27H25F4N9O
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| Canonical SMILES |
C1CN(CCC1N2CC(C2)(CC#N)N3C=C(C=N3)C4=C5C=CNC5=NC=N4)C(=O)NC6=C(C=C(C=C6)F)C(F)(F)F
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| InChI |
1S/C27H25F4N9O/c28-18-1-2-22(21(11-18)27(29,30)31)37-25(41)38-9-4-19(5-10-38)39-14-26(15-39,6-7-32)40-13-17(12-36-40)23-20-3-8-33-24(20)35-16-34-23/h1-3,8,11-13,16,19H,4-6,9-10,14-15H2,(H,37,41)(H,33,34,35)
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| InChIKey |
RZUCZMLSGAQMJN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | TYRO3 tyrosine kinase receptor (TYRO3) | Target Info | Inhibitor | [1] |
| Target's Patent Info | TYRO3 tyrosine kinase receptor (TYRO3) | Target's Patent Info | [1] | |
| References | Top | |||
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| REF 1 | Pyrrolopyrimidine derivatives as TAM inhibitors. US10053465. | |||
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