Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N3DW
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Former ID |
DNC014387
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Drug Name |
5-phenyl-1,3,4-thiadiazole-2(3H)-thione
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Synonyms |
5-Phenyl-1,3,4-thiadiazole-2-thiol; 5585-19-3; 1,3,4-Thiadiazole-2-thiol, 5-phenyl-; L 1542; 2-Mercapto-5-fenil-1,3,4-tiadiazolo [Italian]; 5-Phenyl-1,3,4-thiadiazole-2(3H)-thione; CHEMBL596215; 2-mercapto-5-phenyl-1,3,4-thiadiazole; 2-Mercapto-5-fenil-1,3,4-tiadiazolo; AC1Q7GLK; AC1MHZ9V; SCHEMBL969040; DTXSID40204444; ZTLMHGOWADYAHM-UHFFFAOYSA-N; MolPort-000-932-663; ZINC13532595; MFCD01681863; BDBM50320718; 5-phenyl-1,3,4-thiadiazol-2-thiol; AKOS003056166; MCULE-7311616477; NE54511; LS-150315
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C8H6N2S2
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Canonical SMILES |
C1=CC=C(C=C1)C2=NNC(=S)S2
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InChI |
1S/C8H6N2S2/c11-8-10-9-7(12-8)6-4-2-1-3-5-6/h1-5H,(H,10,11)
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InChIKey |
ZTLMHGOWADYAHM-UHFFFAOYSA-N
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CAS Number |
CAS 5585-19-3
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
BioCyc | (S)-reticuline biosynthesis | |||
Eumelanin biosynthesis | ||||
L-dopachrome biosynthesis | ||||
KEGG Pathway | Tyrosine metabolism | |||
Riboflavin metabolism | ||||
Metabolic pathways | ||||
Melanogenesis | ||||
Pathwhiz Pathway | Riboflavin Metabolism | |||
Tyrosine Metabolism | ||||
WikiPathways | Dopamine metabolism |
References | Top | |||
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REF 1 | New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triaz... Bioorg Med Chem. 2010 Jun 1;18(11):4042-8. |
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