Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0N0JL
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| Former ID |
DIB019757
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| Drug Name |
diphosphoric acid
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| Synonyms |
pyrophosphoric acid; phosphonooxyphosphonic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
H4O7P2
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| Canonical SMILES |
OP(=O)(O)OP(=O)(O)O
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| InChI |
1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)
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| InChIKey |
XPPKVPWEQAFLFU-UHFFFAOYSA-N
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| CAS Number |
CAS 2466-09-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3315, 571608, 596337, 819738, 820211, 820332, 820378, 820380, 820422, 820425, 820430, 820914, 821458, 822446, 823822, 824936, 827919, 828493, 829022, 830805, 830818, 831002, 831009, 832539, 833895, 834879, 835117, 836076, 837458, 837789, 838941, 854579, 854894, 855020, 855049, 855053, 855055, 855259, 4253134, 5315283, 7890028, 8017438, 8025140, 8026543, 8027659, 8028591, 8145399, 8150931, 10318169, 10320630
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| ChEBI ID |
CHEBI:29888
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Geranyltranstransferase (FDPS) | Target Info | Inhibitor | [2] |
| BioCyc | Superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | |||
| Superpathway of cholesterol biosynthesis | ||||
| Trans, trans-farnesyl diphosphate biosynthesis | ||||
| Geranylgeranyldiphosphate biosynthesis | ||||
| KEGG Pathway | Terpenoid backbone biosynthesis | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Influenza A | ||||
| HTLV-I infection | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Cholesterol biosynthesis | |||
| Pathwhiz Pathway | Steroid Biosynthesis | |||
| Reactome | Cholesterol biosynthesis | |||
| Activation of gene expression by SREBF (SREBP) | ||||
| WikiPathways | Activation of Gene Expression by SREBP (SREBF) | |||
| SREBP signalling | ||||
| Cholesterol Biosynthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3151). | |||
| REF 2 | Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of hu... J Med Chem. 2008 Apr 10;51(7):2187-95. | |||
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