Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0MI0Q
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| Drug Name |
Amarylline
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| Synonyms |
Lycorine; BSPBio_0; CHEBI:6601; CHEMBL400092; EINECS 207-503-6; GNF-PF-4974; Galanthidine; (-)-Lycorine; 2188-68-3; 3,2.beta.-diol; I9Q105R5BU; KBioGR_000022; KBioSS_000022; Licorine; Likorin; Lycorine hydrochloride; NSC 401360; NSC401360; NSC683873; Narcissine; UNII-I9Q105R5BU
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| Drug Type |
Small molecular drug
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| Indication | Middle East Respiratory Syndrome (MERS) [ICD-11: 1D64] | Investigative | [1], [2] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL |
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| Formula |
C16H17NO4
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| Canonical SMILES |
C1CN2CC3=CC4=C(C=C3C5C2C1=CC(C5O)O)OCO4
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| InChI |
1S/C16H17NO4/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19/h3-5,11,14-16,18-19H,1-2,6-7H2/t11-,14-,15+,16+/m0/s1
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| InChIKey |
XGVJWXAYKUHDOO-DANNLKNASA-N
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| CAS Number |
CAS 476-28-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:6601
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | MERS-CoV RNA-directed RNA polymerase (RdRp) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | High-Throughput Screening and Identification of Potent Broad-Spectrum Inhibitors of Coronaviruses. J Virol. 2019 May 29;93(12). pii: e00023-19. | |||
| REF 2 | Lycorine: A prospective natural lead for anticancer drug discovery. Biomed Pharmacother. 2018 Nov;107:615-624. | |||
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