Drug Information
Drug General Information | Top | |||
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Drug ID |
D0MG6V
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Drug Name |
3-substituted-1,2,4-oxadiazole derivative 2
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Synonyms |
PMID30107136-Compound-Example34
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Drug Type |
Small molecule immunotherapy
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Indication | Hepatitis [ICD-11: DB97.Z] | Patented | [1] | |
Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] | Patented | [1] | ||
Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139] | Patented | [1] | ||
Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Patented | [1] | ||
Company |
AURIGENE DISCOVERY TECHNOLOGIES LIMITED
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Structure |
Download2D MOL |
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Formula |
C15H16N6O5
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Canonical SMILES |
CC(C(C(=O)O)NC(=O)NC(CC#C)C1=NC(=NO1)C2=NC=CN=C2)O
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InChI |
1S/C15H16N6O5/c1-3-4-9(18-15(25)19-11(8(2)22)14(23)24)13-20-12(21-26-13)10-7-16-5-6-17-10/h1,5-9,11,22H,4H2,2H3,(H,23,24)(H2,18,19,25)/t8?,9-,11-/m0/s1
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InChIKey |
DGLNBPSKIUYJIJ-PCFYAGROSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target Info | Inhibitor | [1] |
Target's Patent Info | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target's Patent Info | [1] |
References | Top | |||
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REF 1 | A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678. |
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