Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M7LA
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| Former ID |
DIB019636
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| Drug Name |
PMID15603962Crac-16
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| Synonyms |
GTPL2333
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL
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| Formula |
C18H14ClF3O4
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| Canonical SMILES |
CC1=C(C(C2=C(C1)COC2=O)C3=CC(=C(C=C3)Cl)C(F)(F)F)C(=O)OC
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| InChI |
1S/C18H14ClF3O4/c1-8-5-10-7-26-17(24)15(10)14(13(8)16(23)25-2)9-3-4-12(19)11(6-9)18(20,21)22/h3-4,6,14H,5,7H2,1-2H3
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| InChIKey |
WMQUFXJLJGXXJD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium-activated potassium channel KCa3.1 (KCNN4) | Target Info | Blocker (channel blocker) | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | IKCa-channel blockers. Part 2: discovery of cyclohexadienes. Bioorg Med Chem Lett. 2005 Jan 17;15(2):401-4. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2333). | |||
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