Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M2PP
|
|||
| Former ID |
DIB021178
|
|||
| Drug Name |
VU0240551
|
|||
| Synonyms |
893990-34-6; VU 0240551; VU0240551; N-(4-Methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]-acetamide; VU0240551-2-D4; N-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide; VU-0240551; n-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide; VU0240551-1; N-(4-methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)thio]acetamide; C16H14N4OS2; C26H30N2O5; N-(4-methyl-1,3-thiazol-2-yl)-2-(6-phenylpyridazin-3-yl)sulfanylacetamide; AC1OHJ6T; MLS000621247; GTPL4665; CHEMBL1491962; SCHEMBL20240442; BDBM43891
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C16H14N4OS2
|
|||
| Canonical SMILES |
CC1=CSC(=N1)NC(=O)CSC2=NN=C(C=C2)C3=CC=CC=C3
|
|||
| InChI |
1S/C16H14N4OS2/c1-11-9-23-16(17-11)18-14(21)10-22-15-8-7-13(19-20-15)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,17,18,21)
|
|||
| InChIKey |
WJRWSLORVIHRNX-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 893990-34-6
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:92476
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Solute carrier family 12 member 5 (SLC12A5) | Target Info | Inhibitor | [2] |
| KEGG Pathway | GABAergic synapse | |||
| Reactome | Cation-coupled Chloride cotransporters | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4665). | |||
| REF 2 | Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5383-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.