Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M1VC
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| Former ID |
DAP001176
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| Drug Name |
Amdinocillin
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| Synonyms |
Coactin; Hexacillin; Mecilinamo; Mecillinam; Mecillinamum; Selexidin; Amdinocillin Mecillinam; Amdinocillin [USAN]; Penicillin HX; FL 1060; Ro 109070; Amdinocillin (USAN); Coactin (TN); FL-1060; Mecilinamo [INN-Spanish]; Mecillinam (INN); Mecillinamum [INN-Latin]; Ro 10-9070; Ro-10-9070; Rel-(2R,6S)-6-{[(1E)-azepan-1-ylmethylene]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-(((Hexahydro-1H-azepin-1-yl)methylene)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid; (2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-[(azepan-1-ylmethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-{[(1E)-azepan-1-ylmethylidene]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-((Hexahydro-1H-azepin-1-yl)methyleneamino)penicillanic acid; 6beta-[(azepan-1-ylmethylidene)amino]-2,2-dimethylpenam-3alpha-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Approved | [1] | |
| Therapeutic Class |
Antibiotics
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| Company |
Leo Pharmaceutical
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| Structure |
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Download2D MOL |
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| Formula |
C15H23N3O3S
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| Canonical SMILES |
CC1(C(N2C(S1)C(C2=O)N=CN3CCCCCC3)C(=O)O)C
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| InChI |
1S/C15H23N3O3S/c1-15(2)11(14(20)21)18-12(19)10(13(18)22-15)16-9-17-7-5-3-4-6-8-17/h9-11,13H,3-8H2,1-2H3,(H,20,21)/t10-,11+,13-/m1/s1
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| InChIKey |
BWWVAEOLVKTZFQ-NTZNESFSSA-N
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| CAS Number |
CAS 32887-01-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
592660, 10823391, 14826403, 17397045, 26719868, 34677751, 37101858, 46386744, 46508450, 48415544, 49681648, 50050811, 56314530, 56314531, 56314532, 56464283, 57288562, 57288563, 57288564, 57311843, 79242042, 92308324, 103175272, 103567509, 104323625, 119525807, 124658876, 124766032, 124899397, 127579795, 134224988, 134338421, 134999918, 137009354, 137021344, 144205762, 160964497, 163125458, 164814666, 165235849, 170465354, 172080246, 176250051, 177749534, 179150325, 179295917, 184546700, 184654349, 198978028, 204369763
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| SuperDrug ATC ID |
J01CA11
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| SuperDrug CAS ID |
cas=032887017
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Penicillin binding protein 2 (Bact mrdA) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drug information of Amdinocillin, 2008. eduDrugs. | |||
| REF 2 | Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation. J Bacteriol. 2008 Jun;190(11):3914-22. | |||
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