Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0LM6A
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| Former ID |
DNC003268
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| Drug Name |
5'-S-ethyl-5'-thioadenosine
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| Synonyms |
5'-S-ethyl-5'-thioadenosine; S-adenosylethane; 5'-ethylthioadenosine; CHEBI:74046; SCHEMBL998091; CHEMBL195660; 5'-Deoxy-5'-(ethylthio)adenosine; DB07052; (2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-[(ethylsulfanyl)methyl]oxolane-3,4-diol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H17N5O3S
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| Canonical SMILES |
CCSCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
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| InChI |
1S/C12H17N5O3S/c1-2-21-3-6-8(18)9(19)12(20-6)17-5-16-7-10(13)14-4-15-11(7)17/h4-6,8-9,12,18-19H,2-3H2,1H3,(H2,13,14,15)/t6-,8-,9-,12-/m1/s1
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| InChIKey |
HMXHURAGFHWODC-WOUKDFQISA-N
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:74046
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosylhomocysteinase (AHCY) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of methionine degradation | |||
| Methionine degradation | ||||
| Cysteine biosynthesis | ||||
| KEGG Pathway | Cysteine and methionine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Selenoamino Acid Metabolism | |||
| Betaine Metabolism | ||||
| Methionine Metabolism | ||||
| WikiPathways | Metabolism of amino acids and derivatives | |||
| Trans-sulfuration and one carbon metabolism | ||||
| One Carbon Metabolism | ||||
| Trans-sulfuration pathway | ||||
| Phase II conjugation | ||||
| Folate Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
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