Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0LG4V
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| Former ID |
DIB008880
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| Drug Name |
SR-47063
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| Synonyms |
SR-47063; SR 47063; 135809-60-8; SCHEMBL3694183; SCHEMBL9205867; sr47063; AC1L3015; 4-(2-Cyanimino-1,2-dihydropyrid-1-yl)-2,2-dimethyl-6-nitrochromene; (1-(2,2-Dimethyl-6-nitro-2H-1-benzopyran-4-yl)-2(1H)-pyridinylidene)cyanamide; [1-(2,2-dimethyl-6-nitrochromen-4-yl)pyridin-2-ylidene]cyanamide; Cyanamide, (1-(2,2-dimethyl-6-nitro-2H-1-benzopyran-4-yl)-2(1H)-pyridinylidene)-
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| Drug Type |
Small molecular drug
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| Indication | Cardiac arrhythmias [ICD-11: BC9Z; ICD-9: 427] | Discontinued in Phase 1 | [1] | |
| Company |
Sanofi
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| Structure |
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Download2D MOL |
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| Formula |
C17H14N4O3
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| Canonical SMILES |
CC1(C=C(C2=C(O1)C=CC(=C2)[N+](=O)[O-])N3C=CC=CC3=NC#N)C
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| InChI |
1S/C17H14N4O3/c1-17(2)10-14(20-8-4-3-5-16(20)19-11-18)13-9-12(21(22)23)6-7-15(13)24-17/h3-10H,1-2H3
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| InChIKey |
ZOHLDHMGABPLCB-UHFFFAOYSA-N
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| CAS Number |
CAS 135809-60-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002328) | |||
| REF 2 | Vasorelaxant effects of the potassium channel opener SR 47063 on the isolated human saphenous vein and rat aorta. Braz J Med Biol Res. 2000 Aug;33(8):961-6. | |||
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