Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0L9QM
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| Former ID |
DIB015886
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| Drug Name |
MK-7145
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| Synonyms |
MK-7145; UNII-M371870BYL; M371870BYL; 1255204-84-2; SCHEMBL2894681; CHEMBL3696475; OCKGFTQIICXDQW-ZEQRLZLVSA-N; BDBM155921; AKOS032946121; DB11968; HY-18277; 5,5'-((1R,1'R)-Piperazine-1,4-diylbis(1-hydroxyethane-2,1-diyl))bis(4-methylisobenzofuran-1(3H)-one); 1(3H)-Isobenzofuranone, 5,5'-(1,4-piperazinediylbis((1R)-1-hydroxy-2,1-ethanediyl))bis(4-methyl-; US9018211, 2A; CS-0007374
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| Drug Type |
Small molecular drug
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Phase 1 | [1] | |
| Company |
Merck
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H30N2O6
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| Canonical SMILES |
CC1=C(C=CC2=C1COC2=O)C(CN3CCN(CC3)CC(C4=C(C5=C(C=C4)C(=O)OC5)C)O)O
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| InChI |
1S/C26H30N2O6/c1-15-17(3-5-19-21(15)13-33-25(19)31)23(29)11-27-7-9-28(10-8-27)12-24(30)18-4-6-20-22(16(18)2)14-34-26(20)32/h3-6,23-24,29-30H,7-14H2,1-2H3/t23-,24-/m0/s1
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| InChIKey |
OCKGFTQIICXDQW-ZEQRLZLVSA-N
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| CAS Number |
CAS 1255204-84-2
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01370655) A Study of MK-7145 Compared to Placebo and Hydrochlorothiazide for Lowering Blood Pressure in Male Participants With Hypertension (MK-7145-009 AM1). U.S. National Institutes of Health. | |||
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