Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0L3JL
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| Drug Name |
Aryl mannoside derivative 8
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| Synonyms |
PMID26651364-Compound-19
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| Drug Type |
Carbohydrates
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| Indication | Crohn disease [ICD-11: DD70; ICD-10: K50, K50.9; ICD-9: 555] | Patented | [1] | |
| Ulcerative colitis [ICD-11: DD71; ICD-9: 556] | Patented | [1] | ||
| Urinary tract infection [ICD-11: GC08; ICD-10: N39, N39.0; ICD-9: 599] | Patented | [1] | ||
| Company |
THE WASHINGTON UNIVERSITY JANETKA, James W. HAN, Zhenfu HULTGREN, Scott PINKNER, Jerry CUSUMANO, Corrine
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Fimbrin D-mannose adhesin (Bact FimH) | Target Info | Antagonist | [1] |
| Target's Patent Info | Bacterial Fimbrin D-mannose adhesin (Bact FimH) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Mannose-derived FimH antagonists: a promising anti-virulence therapeutic strategy for urinary tract infections and Crohn's disease.Expert Opin Ther Pat. 2016;26(2):175-97. | |||
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