Drug Information
Drug General Information | Top | |||
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Drug ID |
D0KX8B
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Former ID |
DIB009618
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Drug Name |
GNE Lipoplex
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Synonyms |
GNE Lipoplex (intramuscular, HIBM-2)
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Indication | Myopathy [ICD-11: 8C7Y] | Phase 1 | [1] | |
Company |
Gradalis
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Target and Pathway | Top | |||
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Target(s) | N-acetylmannosamine kinase (GNE) | Target Info | Inhibitor | [2] |
BioCyc | CMP-N-acetylneuraminate biosynthesis I (eukaryotes) | |||
KEGG Pathway | Amino sugar and nucleotide sugar metabolism | |||
Metabolic pathways | ||||
Pathwhiz Pathway | Amino Sugar Metabolism | |||
Reactome | Sialic acid metabolism |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034673) | |||
REF 2 | Hereditary inclusion body myopathy: single patient response to intravenous dosing of GNE gene lipoplex. Hum Gene Ther. 2011 Nov;22(11):1331-41. |
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