Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0KV6C
|
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| Former ID |
DCL001228
|
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| Drug Name |
RG3039
|
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| Indication | Spinal muscular atrophy [ICD-11: 8B61] | Phase 1 | [1] | |
| Company |
Repligen
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C21H23Cl2N5O
|
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| Canonical SMILES |
C1CN(CCC1COC2=CC=CC3=C2C(=NC(=N3)N)N)CC4=C(C=CC=C4Cl)Cl
|
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| InChI |
1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6,13H,7-12H2,(H4,24,25,26,27)
|
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| InChIKey |
MNLHFGXIUJNDAF-UHFFFAOYSA-N
|
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| CAS Number |
CAS 1005504-62-0
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Scavenger decapping enzyme DcpS (DCPS) | Target Info | Inhibitor | [1] |
| KEGG Pathway | RNA degradation | |||
| WikiPathways | Deadenylation-dependent mRNA decay | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2011 Pipeline of Repligen. | |||
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